Peptide-Based Therapeutics: Developing and Scaling Through Innovative Technologies
11.18.2024
Peptide-based therapeutics are rapidly gaining clinical and commercial success, leading to the need for technologies to develop and scale these candidates. While manufacturing peptide candidates can be complex, the rise of capabilities such as liquid-phase peptide synthesis (LPPS) and the utilization of peptide crystallization can help to develop more cost-efficient and environmentally sustainable manufacturing solutions.
During this webinar, hear from a team of Cambrex experts as they discuss technologies and case studies surrounding LPPS, peptide crystallization, method development for peptide impurity analysis and more.
Key Takeaways/Case Studies to be Discussed:
- Application of liquid-phase peptide synthesis vs. solid-phase peptide synthesis
- Process development workflows for the scalable production of peptide fragment building blocks
- Advantages of peptide crystallization
- Method development for purity and impurities analytics for peptides using a combination of HPLC approaches
- Determination of intact mass and peptide sequencing for identification purposes using LC-MS